At what pH level are most bacteria pathogenic to humans?

The pH range of 7.35 to 7.45 is considered the normal physiological range for human blood and bodily fluids, which is optimal for many pathogenic bacteria. Most pathogenic bacteria that infect humans thrive in environments that closely mimic the natural conditions of the human body, where the neutral to slightly alkaline pH of 7.35 to 7.45 provides an ideal environment for their metabolic processes and growth. This pH range is critical for the virulence of these microorganisms, as it supports various enzymatic and biochemical reactions necessary for their survival and ability to cause disease.

In contrast, the other pH ranges listed are generally too acidic or alkaline for most human pathogens to flourish effectively. For example, a pH of 5.0-5.5 is more acidic and typically supports the growth of certain fungi and some acid-tolerant bacteria, but is not the environment where most pathogenic bacteria thrive. Similarly, a pH of 6.0-6.5 is still on the lower end and may not provide the optimal environment for many pathogens. A pH of 8.0-8.5 is significantly alkaline and again would not typically support the growth of the pathogens that humans are most susceptible to.